Yes. You pay the ENTIRE AMOUNT at the time if booking. The reservation is subject to the sites terms regarding cancellations & changes, so read these terms carefully before hitting the pay button.

IMPORTANT:
As a word to the wise, do not ever use your debit card, check, wire transfer, certified check or cash to pay. Always use a major credit card (I like American Express) so if there is ever a serious problem with the hotel, or the reservation in general, you can file a complaint with your credit card company to reverse the charge.

If you pay by other debit card, they take the money out of your bank account immediately. It is like cash and you're going to have very little recourse or leverage to get your money back.

Hope this advise helps.

I'm an hotel owner, is right you'll be charged right the way, and you know that booking.com will pass to the hotel all your credit card details, I mean all...

Yes you will. I learned my lesson using booking.com and did not want to use my credit card. They take your money with no problem but need proof of payment when you need a refund. Seems like they have more and more issues with people not getting their hotels or not getting their money back. This company is a scam and should be put out of business.

Yes you will be charged when you book

Yep I would think so. Try travel Republic. You can pay a pound deposit on most rooms
Great service as well. I wouldn't go near booking. Com