Replenex extra strength has been my personal life saver. I have an extreme case of full body arthritis, especially effecting my neck, shoulders and hands. For the past five years I have just been dealing with the never ending dull pain that no other medications have been able to touch. Last year I was introduced to Melaleuca and had done some research on many of their products and decided to try replenex es. With in three days the pain in my neck and shoulders was greatly decreased and I had better mobility in my hands. I have been taking it now for three months and have zero pain and can sleep once again. Thank you Melaleuca!