I love this product. I have been taking DigestiCure Autoimune-X since 12/1/14. I ran out for 2 weeks during the Covid Christmas shipping debacle and the pain in my joints were beginning again. So, when I received it, I started on the full dose until the pain went away and then leveled back down to 4 pills per day. I was diagnosed with Lupus in 1999. My last blood test finally shows "negative". However, the blood test really doesn't matter to me. What does matter is...I feel great with no joint pain! The pain was managed within 6 months of starting on it