I find series get married to certain characters or a story line until I just have to stop watching.
They fall into a rut with characters that should die or go away but don't. They also drag out a storyline for too many episodes. You other writers out there need to break it up more.
The same thing happens in supernatural but just before you say enough is enough the characters die or disappear. They also take a storyline that is getting dragged out and just drop it and may or may not address it in some future episode.