Shop.com has some of the best support products for your health that you can find anywhere. Because they are a brokerage, they work with the best manufacturers that have superb patents, like their Isotonic Resveratrol. It has 3 patents in it! Resveravene, BioVin, and VitaBlue. An in vitro study showed that Resveravene was more efficient on SIRT-1* activation, therefore may have a positive effect on life span extension. And the product is isotonic!