From my experience, Hangout sucks. I work remotely with a team of three other people, and one person with a relatively new MacBook Air constantly has issues with getting his camera working with it. Plus there is its annoying habit of deciding when to mute or unmute you, which wouldn't be so bad if there was a way to switch it back without being focused in the Hangout window.
In fact, we have gotten so fed up with Hangouts that we are moving TO Skype. One person is going to get a premium account, which will allow us to duplicate most of what we use Hangouts for.